Should I Be Worried If My B12 Is High?

Can fatty liver cause high b12 levels?

The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters.

Results: Vitamin B12 levels were significantly lower in patients with NAFLD.

Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels..

What is the treatment for high vitamin b12?

In many older adults, the secretion of hydrochloric acid in the stomach is reduced, causing a reduction in the absorption of vitamin B12. If your body has difficulty absorbing vitamin B12, your doctor may recommend intramuscular injections of B12 to increase your levels.

What is considered a high b12 level pmol L?

High serum vitamin B12 is defined by a rate above 950 pg/ml (701 pmol/l), which corresponds by biological standards, to the upper limit of biological normality, in the absence of any sign and/or clinical anomaly.

Why is my b12 over 2000?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.

What is optimal b12 level?

The vitamin B12 standard reference range is 200–700 pg/ml whereas the proposed optimal range is 500–1300 pg/ml [10]. Higher vitamin B12 ranges have been associated with increased cognitive function, and reflexes, decreased brain atrophy, confusion, weakness and depression [10].

How can I check my b12 level at home?

There are several ways to test your B-12 levels. You can get your blood drawn or take a home urine test. These tests will look at the levels of your: overall vitamin B-12.

What is normal level of vitamin b12 in elderly?

Although MedlinePlus says that “Normal values are 160 to 950 picograms per milliliter (pg/mL)”, the clinical reference UptoDate says that a normal serum vitamin B12 level is above 300 pg/mL. If the vitamin B12 level is borderline, a confirmatory blood test can be ordered.

Can Vitamin b12 hurt your liver?

In doses over 1,200 IU per day, vitamin E can thin the blood and cause bleeding. Vitamin B12 is the only B-complex vitamin and water-soluble vitamin that can be stored in the liver, where it can remain for years, notes the University of Maryland Medical Center.

Why would my b12 be high?

Usually, excess vitamin B12 is removed in the urine. Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)

What is a normal b12 level for a woman?

Understanding the Results But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.

Can you have high b12 levels and still be deficient?

Serum B12 can be false normal or even false high, while a deficiency is present. A value above the reference value does not automaticcaly rule out a deficiency and a (slightly) lower value does not automatically mean a B12 deficiency, although a B12 value beneath 150 pmol/L has a specificity of 95% or more.

Is High b12 serious?

Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.

Can Vitamin b12 damage your liver?

Some studies have indicated that elevated serum levels of vitamin B12 might be a sign of a serious and life-threatening disease. Such falsely high valued of serum vitamin B12 levels are observed in myeloproliferative disease, acute hepatitis, severe alcoholic liver disease, and cirrhosis.

What are the neurological symptoms of b12 deficiency?

A lack of vitamin B12 can cause neurological problems, which affect your nervous system, such as:vision problems.memory loss.pins and needles (paraesthesia)loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking.More items…

What happens if your b12 is too high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

Is b12 level of 1000 too high?

There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.

How do I lower my vitamin b12?

As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

Can anemia cause high b12?

A low level of vitamin B12 in the blood indicates pernicious anemia. However, a falsely normal or high value of vitamin B12 in the blood may occur if antibodies interfere with the test. Your homocysteine and methylmalonic acid (MMA) levels. High levels of these substances in your body are a sign of pernicious anemia.

Can low b12 cause hair loss?

When vitamin B12 levels are low, your hair follicles may not be able to grow new hair as efficiently, resulting in hair loss. A vitamin B12 deficiency can also cause symptoms of anemia, which is associated with low iron levels, hair thinning, and hair loss.

Can hypothyroidism cause high b12 levels?

Research shows that there is a high prevalence — approximately 40% — of B12 deficiency in hypothyroid and Hashimoto’s patients. This prevalence may be due to the high association between anemia and hypothyroidism.