Quick Answer: What Are The Top 10 Rarest Diseases?

What are the most common rare diseases?

What Are Rare Diseases?Multiple sclerosis emerges above all others, at 90 patients per 100,000 people.Narcolepsy—intermittent, uncontrollable episodes of sleepiness—affects 50 patients per 100,000.Primary biliary cholangitis, the damage of bile ducts in the liver, affects 40 people in 100,000.More items…•.

What is the strangest disease?

Water allergy.Foreign accent syndrome.Laughing Death.Fibrodysplasia ossificans progressiva (FOP)Alice in Wonderland syndrome.Porphyria.Pica.Moebius syndrome.More items…•

What are examples of rare diseases?

Examples of rare diseases caused by mutations in single genes include cystic fibrosis, which affects the respiratory and digestive systems (See: Learning About Cystic Fibrosis); Huntington’s disease, which affects the brain and nervous system (See: Learning About Huntington’s Disease); and muscular dystrophies, which …

Can you have a disease without knowing?

But sometimes, you can be sick without even knowing it — whether you have a viral infection like the flu or a chronic condition like high blood pressure. These types of illnesses are called asymptomatic, meaning they present without symptoms.

How many diseases are there in human body?

There are four main types of disease: infectious diseases, deficiency diseases, hereditary diseases (including both genetic diseases and non-genetic hereditary diseases), and physiological diseases.

What are the 7000 rare diseases?

You can find a list of all the 7,000+ rare diseases on the Orphanet website.Fibrodysplasia ossificans progressiva. Prevalence: roughly 1 in 2,000,000. … Ehlers Danlos syndrome. Prevalence: Unknown. … Tyrosinemia type 1. Prevalence: Unknown. … Duchenne muscular dystrophy. … Cystic fibrosis. … NGLY-1 deficiency.

What is the rarest mental disorder?

Apotemnophilia. Also known as body integrity identity disorder, apotemnophilia is characterized by the “overwhelming desire to amputate healthy parts of [the] body,” according to Medscape. Though not much is known about it, this disorder is believed to be neurological.

What are 5 genetic diseases?

What You Need to Know About 5 Most Common Genetic DisordersDown Syndrome. Typically, the nucleus of an individual cell contains 23 pairs of chromosomes, but Down syndrome occurs when the 21st chromosome is copied an extra time in all or some cells. … Thalassemia. … Cystic Fibrosis. … Tay-Sachs disease. … Sickle Cell Anemia. … Learn More. … Recommended. … Sources.

Is depression classified as a disease?

Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems.

How do I know if I am mentally ill?

Examples of signs and symptoms include:Feeling sad or down.Confused thinking or reduced ability to concentrate.Excessive fears or worries, or extreme feelings of guilt.Extreme mood changes of highs and lows.Withdrawal from friends and activities.Significant tiredness, low energy or problems sleeping.More items…•

What’s a rare degenerative disease?

Creutzfeldt-Jakob disease (CJD) is an extremely rare degenerative brain disorder (i.e., spongiform encephalopathy) characterized by sudden development of rapidly progressive neurological and neuromuscular symptoms.

What is the most rarest disease in the world?

RPI deficiency According to the Journal of Molecular Medicine, Ribose-5 phosphate isomerase deficiency, or RPI Deficinecy, is the rarest disease in the world with MRI and DNA analysis providing only one case in history.

What is the most difficult disease to diagnose?

Conditions That Are Hard to Diagnose7 / 14. Lyme Disease. … 8 / 14. Fibromyalgia. … 9 / 14. Lupus. … 10 / 14. Parkinson’s Disease. … 11 / 14. Multiple Sclerosis (MS) … 12 / 14. Chronic Fatigue Syndrome. … 13 / 14. Polycystic Ovary Syndrome (PCOS) … 14 / 14. Endometriosis. This happens when the tissue that lines a woman’s uterus grows outside of it.More items…

What disease has no cure?

HIV/AIDS – No cure exists for HIV/AIDS, but medication exists that can help control the symptoms of it. Huntington’s disease – Inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain. Hydrocephalus – No cure exists for this (physical)neurological disorder.

What disease kills you slowly?

What is Huntington’s disease? Huntington’s disease is a rare, progressive brain disorder. It gradually kills nerve cells in the brain. This slowly deteriorates a person’s physical and mental abilities.

How often do doctors get it wrong?

Studies of autopsies have shown that doctors seriously misdiagnose fatal illnesses about 20 percent of the time. So millions of patients are being treated for the wrong disease. As shocking as that is, the more astonishing fact may be that the rate has not really changed since the 1930’s.

What diseases make you go crazy?

Related to SchizophreniaAnxiety/Panic Disorders.Bipolar Disorder.Mental Health.Psychotic Depression.Schizoaffective Disorder.Schizophreniform Disorder.Smoking Cessation.

How many rare diseases are genetic?

There are between 5 000 and 8 000 rare diseases, most of them with a genetic basis. 1 A very rough estimate would be that one out of 15 persons worldwide could be affected by a rare (“orphan”) disease – 400 million people worldwide, of whom 30 million are in Europe and 25 million in the United States.

Is Groat’s Syndrome Real?

GROAT’S SYNDROME/GROAT’S DISEASE Rob Reiner asks Larry to participate in a charity auction to raise money to help fight this ailment: a fictitious neurological disorder, marked by excessive hyperactivity and spasticity.

What is TUGO disease?

Degos disease is an extremely rare disorder in which small and medium sized arteries become blocked (occlusive arteriopathy), restricting the flow of blood to affected areas. Degos disease usually causes characteristic skin lesions that may last for a period of time ranging from weeks to years.

What is the hardest mental illness to live with?

Why Borderline Personality Disorder is Considered the Most “Difficult” to Treat. Borderline personality disorder (BPD) is defined by the National Institute of Health (NIH) as a serious mental disorder marked by a pattern of ongoing instability in moods, behavior, self-image, and functioning.